Molecular Templates Inc
  • Austin, TX, USA
  • Full Time

Company Description:

Molecular Templates is a clinical stage biopharmaceutical company focused on the discovery and development of differentiated, targeted, biologic therapeutics for cancer. We believe our proprietary biologic drug platform technology, referred to as engineered toxin bodies, or ETBs, provides a differentiated mechanism of action that may address some of the limitations associated with currently available cancer therapeutics. ETBs utilize a genetically engineered form of Shiga-like Toxin A subunit, or SLTA, a ribosome inactivating bacterial protein, that can be targeted to specifically destroy cancer cells. Additional information about Molecular Templates can be obtained at

Position Overview:

Molecular Templates is seeking a highly skilled and highly motivated professional to support novel protein-based therapeutics manufacturing activities. The Supervisor will be responsible for implementing the manufacturing processes, identifying opportunities for process improvement and assisting in process development, quality control, and tech transfer.  The Supervisor will oversee the day to day operation of a production group. The Supervisor will be responsible for training activities and material release. This position will require excellent technical, analytical and problem-solving skills, along with the ability to operate independently and lead complex activities and projects.

Job Responsibilities will include:

  • Supervise and coordinate the activities of personnel engaged in mid-scale manufacturing of protein-based therapeutics with a focus of downstream operations
  • Implement manufacturing processes and test manufacturing technologies and products
  • Perform batch release, support quality control, and process development activities
  • Assign, check and monitor assignments of team members
  • Investigate, trouble shoot and report on manufacturing deviations
  • Generate protocols, SOPs and production reports
  • Order, stock and track the lab inventory and maintain lab equipment and spaces
  • Train new and existing employees on protein production processes
  • Maintain knowledge of scientific trends and industry processes through readings, conferences and seminars; review literature to enhance or improve manufacturing procedures and methods. Use professional concepts and company policies and procedures to solve a wide range of difficult problems in creative and practical ways
  • Other duties and special projects, as assigned


  • Master's degree in Life sciences, chemical engineering, biochemical engineering or related relevant field
  • Minimum of four (4) years of relevant experience producing pre-clinical drug products and conducting early stage process development biologics drug substance processes, required
  • Minimum of one (1) year supervising direct reports
  • Experience in biopharmaceutical industry, required
  • Experience with bacterial fermentation (USP), required
  • Hands-on experience with modern fermenters and bioreactors, preferred
  • Experience of protein purification of biologics (DSP) at mid-large scale in pharma or biotech sector, required
  • Experience with antibody-based protein production, immunotoxins and/or recombinant fusion proteins, preferred
  • Experience writing, updating and training SOP driven processes
  • Excellent management skills
  • Excellent written and verbal communication skills
  • Excellent computer skills
  • Excellent analytical skills and problem-solving skills
  • Excellent organizational, time management, and multi-tasking skills
  • Ability to train and schedule lab based direct reports
  • Ability and willingness to work at the bench for variable percentage of time
  • Ability to review and release batch records
  • Ability to maintain highest standards of accuracy and attention to detail
  • Ability to function independently and exercise good judgement, as well as provide thought leadership
  • Ability to identify problems and solutions then act to resolve
  • Ability to work in a fast-paced, high-growth, and team-based environment

Reporting Structure:

This position currently has supervisory responsibilities. This position reports to Director, Protein Sciences.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc
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