Molecular Templates Inc
  • Austin, TX, USA
  • Full Time

Company Description:

Molecular Templates is a clinical stage biopharmaceutical company focused on the discovery and development of differentiated, targeted, biologic therapeutics for cancer. We believe our proprietary biologic drug platform technology, referred to as engineered toxin bodies, or ETBs, provides a differentiated mechanism of action that may address some of the limitations associated with currently available cancer therapeutics. ETBs utilize a genetically engineered form of Shiga-like Toxin A subunit, or SLTA, a ribosome inactivating bacterial protein, that can be targeted to specifically destroy cancer cells. Additional information about Molecular Templates can be obtained at


Position Overview:

Molecular Templates is seeking an experienced and dynamic professional to manage and direct the design and scale-up of processes, instruments and equipment from the laboratory through pilot plant and manufacturing at both internal and external manufacturing sites.


Job Responsibilities will include:

  • Oversee day to day operations of Upstream Development
  • Design, execute and analyze fermentation development experiments independently
  • Designs robust and scalable upstream processes using scientific and engineering principles
  • Transfer technology to internal and external manufacturing partners
  • Plan and implement the development of new process formulas
  • Establish operation equipment specifications and may improve manufacturing techniques and new process equipment production
  • Designs, manages and supports process characterization studies and develops control strategies for process validation
  • Works effectively with team members and contractors both in-person and remotely. Provides direction, support, and corrective action as needed.
  • Ensures that all processes are in line with health, safety, environmental and quality requirements including regulations, policies, applicable guidelines and procedures.
  • May require travel up to 25%



  • PhD in Chem Engineering, Microbiology or closely related field plus, 7+ years experience in fermentation process development
  • Strong experience in statistically designed experiments
  • Experienced in tech transfer of a process from development to manufacturing or between manufacturing sites
  • Experience managing multiple direct reports
  • Downstream processing experience preferred
  • Biopharmaceutical experience strongly preferred
  • Outstanding knowledge, and ability to apply scientific principles utilized to solve operational, as well as routine production tasks
  • Excellent documentation skills including comprehension, review & establishing Batch Production Records, SOP's, deviation & summary reports


Reporting Structure:

This position currently has supervisory responsibilities. This position reports to Director, Upstream Development.


Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc
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